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C2HF3O2/c8-4(1-2-5(10)11)7(14)9-3-6(12)13
5-dihydro-1H-pyrrol-1-yl)amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate
β-naloxol β-naloxamine
LCZ696 has a formula as (valsartan)(sacubitril)(3Sodium)(5/2 hydrate)
Chemical Name: 4-(3-methyl-2-oxobutoxy)-7H-furo[3
OXA-01 Catalog No.:M22527-C C2HF3O2/c8-4(1-2-5(10)11)7(14)9-3-6(12)13OXA 01 is an ATP competitive and selective inhibitor of both mTORC1 and mTORC2 with IC50 values of 29 nM and 7 nM, respectively . The mammalian target of rapamycin (mTOR) is a serine threonine kinase and exists in two complexes, mTORC1 and mTORC2. MTORC1 activation through PI3K and Akt controls cell growth and mTORC2 phosphorylates Akt, SGK1, and PKC to control cell survival and cytoskeletal organization . OXA 01 is a dual inhibitor of mTORC1 and
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