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Formula: C26H20Cl5FN2O2
Anti-proliferation effects
Chemical Name: 5-[2-(dimethylamino)ethoxy]-N-{3-[4-(hydroxycarbamoyl)phenyl]prop-2-yn-1-yl}-1H-indole-2-carboxamide
3R)-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoic acid
it against Plasmodium falciparum and E
PF-3450074 60276 Formula: C26H20Cl5FN2O2PF 3450074 (PF 74) is a specifical inhibitor of HIV 1 capsid protein (CA) and displays a broad spectrum inhibition of HIV isolates with submicromolar potency (EC50=8 640 nM). PF 3450074 (PF 74) acts at an early stage of HIV 1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. CPSF6: nuclear host factors
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