GSK 366 Size:Contact [email protected] for quotation Indirubin-3'-monoxime completely inhibits the phosphorylation

Indirubin-3'-monoxime completely inhibits the phosphorylation of the AT100 epitope

Chemical Name: 4-({2-[4-(2-chlorophenyl)piperazine-1-carbonyl]-1-[2-(dimethylamino)ethyl]-1H-indol-3-yl}(4-hydroxyphenyl)methyl)phenol

InChi: InChI=1S/C189H284N54O56S/c1-15-95(8)149(179(293)233-129(82-141(192)252)167(281)224-123(74-93(4)5)163(277)225-124(75-94(6)7)170(284)238-150(100(13)246)180(294)221-120(31-21-66-207-189(201)202)184(298)242-70-25-35-139(242)176(290)219-115(30-20-65-206-188(199)200)156(270)222-121(151(194)265)77-102-39-49-108(248)50-40-102)237-171(285)127(80-105-45-55-111(251)56-46-105)228-166(280)128(81-106-87-203-91-209-106)229-158(272)114(29-19-64-205-187(197)198)217-162(276)122(73-92(2)3)223-154(268)97(10)211-172(286)134(89-244)235-165(279)126(79-104-43-53-110(250)54-44-104)227-164(278)125(78-103-41-51-109(249)52-42-103)226-157(271)113(28-18-63-204-186(195)196)215-152(266)96(9)210-155(269)118(61-72-300-14)218-168(282)131(85-147(261)262)231-160(274)117(58-60-145(257)258)216-153(267)98(11)212-175(289)137-33-23-67-239(137)181(295)99(12)213-161(275)130(84-146(259)260)230-159(273)116(57-59-144(255)256)214-143(254)88-208-174(288)136-32-22-69-241(136)185(299)133(83-142(193)253)234-169(283)132(86-148(263)264)232-177(291)140-36-26-71-243(140)183(297)119(27-16-17-62-190)220-173(287)135(90-245)236-178(292)138-34-24-68-240(138)182(296)112(191)76-101-37-47-107(247)48-38-101/h37-56

has been found to show moderate antioxidant activity (IC(50) 13 microM in DPPH radical scavenging

1H3/b8-7+/t12-/m0/s1

GSK 366 Size:Contact [email protected] for quotation Indirubin-3'-monoxime completely inhibits the phosphorylationGSK 366 is a potent kynurenine 3 monooxygenase (KMO) inhibitor with IC50s of 2. 3 nM and 0. 7 nM for human KMO and P. fluorescens KMO (Pf KMO), respectively. Product information CAS Number: 1953157 39 5 Molecular Weight: 361. 78 Formula: C17H16ClN3O4 Chemical Name: 3 {5 chloro 6 [(1R) 1 (6 methylpyridazin 3 yl)ethoxy] 1,2 benzoxazol 3 yl}propanoic acid Smiles: CC1=CC=C(N=N1)[C@@H](C)OC1=CC2ON=C(CCC(O)=O)C=2C=C1Cl InChiKey: YWASLAPMFGBZQP SNVBAGLBSA N